Campto (irinotecan) chemotherapy drug used to treat colon cancer. This topoisomerase inhibitor is a cytotoxic drug because it interferes with the DNA Stock Photo - Alamy
Temozolomide and irinotecan (TEMIRI regimen) as salvage treatment of irinotecan-sensitive advanced colorectal cancer patients bearing MGMT methylation - Annals of Oncology
Cancers | Free Full-Text | Newly Obtained Apple Pectin as an Adjunct to Irinotecan Therapy of Colorectal Cancer Reducing E. coli Adherence and β-Glucuronidase Activity
Calcitriol enhances the antitumor activity of irinotecan in colon... | Download Scientific Diagram
Irinotecan and Oxaliplatin Might Provide Equal Benefit as Adjuvant Chemotherapy for Patients with Resectable Synchronous Colon Cancer and Liver-confined Metastases: A Nationwide Database Study | Anticancer Research
LEF1 silencing sensitizes colorectal cancer cells to oxaliplatin, 5-FU, and irinotecan - ScienceDirect
Irinotecan: 25 years of cancer treatment - ScienceDirect
Frontiers | Establishment and Characterization of an Irinotecan-Resistant Human Colon Cancer Cell Line
Cell Line Derived 5-FU and Irinotecan Drug-Sensitivity Profiles Evaluated in Adjuvant Colon Cancer Trial Data | PLOS ONE
Cell Line Derived 5-FU and Irinotecan Drug-Sensitivity Profiles Evaluated in Adjuvant Colon Cancer Trial Data | PLOS ONE
Guidelines Consider Use of Targeted Therapies in Colorectal Cancer
Cost–effectiveness of UGT1A1 genotyping in second-line, high-dose, once every 3 weeks irinotecan monotherapy treatment of colorectal cancer | Pharmacogenomics
Effect of drug metabolizing enzymes and transporters in Thai colorectal cancer patients treated with irinotecan-based chemotherapy | Scientific Reports
Irinotecan plus Fluorouracil and Leucovorin for Metastatic Colorectal Cancer | NEJM
Irinotecan-induced cytotoxicity to colon cancer cells in vitro is stimulated by pre-incubation with trifluorothymidine - European Journal of Cancer
Irinotecan Chemotherapy Drug To Treat Colon Cancer | Onco.com
Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells | Molecular Cancer | Full Text
SN-38 (NK012) is an Active Metabolite of the Topoisomerase I Inhibitor Irinotecan - Network of Cancer Research
Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells
Benefits & Risks of Treatment | Metastatic Colorectal Cancer (mCRC)| Avastin® (bevacizumab)
DEP® irinotecan synergistic with Lynparza® in refractory human colon cancer model - Starpharma
Improving Sensitivity to Irinotecan Using 5-Azacytidine in Colon Cancer Cell Lines - Journal of Surgical Research
Drug resistance and new therapies in colorectal cancer
Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review
Randomized study of weekly irinotecan plus high-dose 5-fluorouracil (FUIRI) versus biweekly irinotecan plus 5-fluorouracil/leucovorin (FOLFIRI) as first-line chemotherapy for patients with metastatic colorectal cancer: a Spanish Cooperative Group for ...
6-Shogaol enhances the anticancer effect of 5-fluorouracil, oxaliplatin, and irinotecan via increase of apoptosis and autophagy in colon cancer cells in hypoxic/aglycemic conditions | BMC Complementary Medicine and Therapies | Full Text
